Endocrine Abstracts

Introduction: Primary hyperparathyroidism is associated with insulin resistance and reduced pancreatic beta cell function. Approximately 40% of patients with primary hyperparathyroidism have impaired glucose tolerance. This observational study sought to show improvement in insulin resistance after parathyroidectomy in patients with primary hyperparathyroidism.Methods: Insulin resistance and pancreatic beta-cell function was calculated before and 12 weeks...

Objective: To determine the incidence of osteopaenia and osteoporosis in primary hyperparathyroidism.Methods: Retrospective review of 80 patients with primary hyperparathyroidism; Bone densitometry of the femoral neck, lumbar spine and distal ulna was assessed by dual energy X-ray absorptiometry (DEXA) at the time of diagnosis.Results: The median age at diagnosis was 68; The male: female ratio was 1:3; osteoporosis was present in 2...

Aims: Testosterone treatment is controversial as long-term outcome data are not available; however prescriptions for testosterone are becoming more common.We looked at the symptoms on presentation, indications for testosterone replacement, forms of testosterone replacement, and adherence to present guidelines for monitoring.Methods: Data was collected from case notes of 47 patients on testosterone replacement attending endocrine cl...